FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term beta-glucuronidase activity ID (Ontology) GO:0004566 (Gene Ontology)
Definition Catalysis of the reaction: a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate.[ EC:3 ]
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Gene Groups Genes
 beta-glucuronidase activity (all annotations which use CV term, excluding "NOT" statements)       1      2
     enables | beta-glucuronidase activity       --       2
Spanning Tree (Parents/Children)
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  hydrolase activity, hydrolyzing O-glycosyl compounds
   |__glucuronidase activity
       |__beta-glucuronidase activity  3 rec.
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Is a glucuronidase activity
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Synonyms
  • "beta-D-glucuronoside glucuronosohydrolase activity" RELATED[ EC:3 ]
    "beta-glucuronide glucuronohydrolase activity" RELATED[ EC:3 ]
    "exo-beta-D-glucuronidase activity" RELATED[ EC:3 ]
    "glucuronidase activity" RELATED[ EC:3 ]
    "ketodase activity" RELATED[ EC:3 ]
Secondary IDs
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EC:3.2.1.31
MetaCyc:BETA-GLUCURONID-RXN
Reactome:R-HSA-1678854 "GUSB tetramer hydrolyses CS/HS precursor"
Reactome:R-HSA-2162226 "GUSB tetramer hydrolyzes GlcA-1,3-GlcNAc"
Reactome:R-HSA-2162227 "GUSB tetramer hydrolyses (HA)2"
Reactome:R-HSA-2318373 "Defective GUSB does not hydrolyse (HA)2"
Reactome:R-HSA-9036068 "Defective GUSB does not hydrolyse GlcA-1,3-GlcNAc"
Reactome:R-HSA-9036070 "Defective GUSB does not hydrolyse CS/HS precursor"
RHEA:17633
RHEA:28326
RHEA:30475
RHEA:76111