FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term Glc3Man9GlcNAc2 oligosaccharide glucosidase activity ID (Ontology) GO:0004573 (Gene Ontology)
Definition Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).[ EC:3 ]
Also Known As "mannosyl-oligosaccharide glucosidase (processing A-glucosidase I) activity" ; "trimming glucosidase I"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 Glc3Man9GlcNAc2 oligosaccharide glucosidase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | Glc3Man9GlcNAc2 oligosaccharide glucosidase activity       1
Spanning Tree (Parents/Children)
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  glucosidase activity
   |__alpha-glucosidase activity
       |__Glc3Man9GlcNAc2 oligosaccharide glucosidase activity  1 rec.
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Is a alpha-glucosidase activity
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Synonyms
  • "mannosyl-oligosaccharide glucohydrolase activity" RELATED[ EC:3 ]
    "mannosyl-oligosaccharide glucosidase (processing A-glucosidase I) activity" EXACT
    "mannosyl-oligosaccharide glucosidase activity" RELATED[ EC:3 ]
    "processing A-glucosidase I activity" RELATED[ EC:3 ]
    "trimming glucosidase I" EXACT[ EC:3 ]
Secondary IDs
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EC:3.2.1.106
MetaCyc:3.2.1.106-RXN
Reactome:R-HSA-4793947 "Defective MOGS does not cleave glucose from an N-glycosylated protein"
Reactome:R-HSA-532678 "Trimming of the first glucose by by mannosyl-oligosaccharide glucosidase"
Reactome:R-HSA-9694364 "N-glycan glucose trimming of Spike"
Reactome:R-HSA-9932344 "MOGS removes terminal glucose from Glu3Man9GlcNAc2-CDH1"
RHEA:55988