FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term dolichyl-diphosphooligosaccharide-protein glycotransferase activity ID (Ontology) GO:0004579 (Gene Ontology)
Definition Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine.
Also Known As"asparagine N-glycosyltransferase activity" ; "dolichyl-diphosphooligosaccharide-protein glycosyltransferase activity" ; "dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase activity" (for all, see Synonyms field below)
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 dolichyl-diphosphooligosaccharide-protein glycotransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | dolichyl-diphosphooligosaccharide-protein glycotransferase activity       --
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  hexosyltransferase activity
   |__oligosaccharyl transferase activity
       |__dolichyl-diphosphooligosaccharide-protein glycotransferase activity  5 rec.
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Is a oligosaccharyl transferase activity
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Synonyms
  • "asparagine N-glycosyltransferase activity" EXACT
    "dolichyl-diphosphooligosaccharide-protein glycosyltransferase activity" EXACT
    "dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase activity" EXACT
    "dolichyldiphosphooligosaccharide-protein glycosyltransferase activity" EXACT
    "dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase activity" EXACT
    "dolichyldiphosphoryloligosaccharide-protein oligosaccharyltransferase activity" EXACT
    "dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase activity" EXACT
    "oligomannosyltransferase activity" RELATED
Secondary IDs
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EC:2.4.99.18
MetaCyc:RXN-16761
Reactome:R-HSA-446209 "Transfer of N-glycan to the protein"
Reactome:R-HSA-9694793 "Spike protein gets N-glycosylated"
Reactome:R-HSA-9816276 "CDH1 is N-glycosylated on asparagine residues in endoplasmic reticulum"
Reactome:R-HSA-9918962 "E is N-glycosylated"
Reactome:R-HSA-9918988 "pre-M is N-glycosylated"
Reactome:R-HSA-9919011 "Pre-NS1 folds and is N-glycosylated"
Reactome:R-HSA-9931286 "CD274 N-linked glycosylation in ER"
RHEA:22980
RHEA:50348