FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term orotate phosphoribosyltransferase activity ID (Ontology) GO:0004588 (Gene Ontology)
Definition Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.[ EC:2 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 orotate phosphoribosyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | orotate phosphoribosyltransferase activity
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  glycosyltransferase activity
   |__pentosyltransferase activity
       |__orotate phosphoribosyltransferase activity  1 rec.
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Is a pentosyltransferase activity
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Synonyms
  • "OPRT activity" RELATED[ EC:2 ]
    "OPRTase activity" RELATED[ EC:2 ]
    "orotate phosphoribosyl pyrophosphate transferase activity" RELATED[ EC:2 ]
    "orotic acid phosphoribosyltransferase activity" RELATED[ EC:2 ]
    "orotidine 5'-monophosphate pyrophosphorylase activity" RELATED[ EC:2 ]
    "orotidine monophosphate pyrophosphorylase activity" RELATED[ EC:2 ]
    "orotidine phosphoribosyltransferase activity" RELATED[ EC:2 ]
    "orotidine-5'-phosphate diphosphorylase activity" RELATED[ EC:2 ]
    "orotidine-5'-phosphate pyrophosphorylase activity" RELATED[ EC:2 ]
    "orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase activity" RELATED[ EC:2 ]
    "orotidylate phosphoribosyltransferase activity" RELATED[ EC:2 ]
    "orotidylate pyrophosphorylase activity" RELATED[ EC:2 ]
    "orotidylic acid phosphorylase activity" RELATED[ EC:2 ]
    "orotidylic acid pyrophosphorylase activity" RELATED[ EC:2 ]
    "orotidylic phosphorylase activity" RELATED[ EC:2 ]
    "orotidylic pyrophosphorylase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.4.2.10
MetaCyc:OROPRIBTRANS-RXN
Reactome:R-HSA-73567 "UMPS dimer transfers phosphoribosyl group to ORO to form OMP"
RHEA:10380