FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term orotidine-5'-phosphate decarboxylase activity ID (Ontology) GO:0004590 (Gene Ontology)
Definition Catalysis of the reaction: H+ + orotidine 5'-phosphate = CO2 + UMP.[ EC:4 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 orotidine-5'-phosphate decarboxylase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | orotidine-5'-phosphate decarboxylase activity
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  carbon-carbon lyase activity
   |__carboxy-lyase activity
       |__orotidine-5'-phosphate decarboxylase activity  1 rec.
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Is a carboxy-lyase activity
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Synonyms
  • "ODCase activity" RELATED[ EC:4 ]
    "OMP decarboxylase activity" RELATED[ EC:4 ]
    "OMP-DC" RELATED[ EC:4 ]
    "OMPdcase activity" RELATED[ EC:4 ]
    "orotate decarboxylase activity" RELATED[ EC:4 ]
    "orotate monophosphate decarboxylase activity" RELATED[ EC:4 ]
    "orotic decarboxylase activity" RELATED[ EC:4 ]
    "orotidine 5'-phosphate decarboxylase activity" RELATED[ EC:4 ]
    "orotidine monophosphate decarboxylase activity" RELATED[ EC:4 ]
    "orotidine phosphate decarboxylase activity" RELATED[ EC:4 ]
    "orotidine-5'-monophosphate decarboxylase activity" RELATED[ EC:4 ]
    "orotidine-5'-phosphate carboxy-lyase (UMP-forming)" RELATED[ EC:4 ]
    "orotidine-5'-phosphate carboxy-lyase activity" RELATED[ EC:4 ]
    "orotidylic acid decarboxylase activity" RELATED[ EC:4 ]
    "orotidylic decarboxylase activity" RELATED[ EC:4 ]
    "orotodylate decarboxylase activity" RELATED[ EC:4 ]
    "UMP synthase activity" RELATED[ EC:4 ]
    "uridine 5'-monophosphate synthase activity" RELATED[ EC:4 ]
Secondary IDs
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EC:4.1.1.23
KEGG_REACTION:R00965
MetaCyc:OROTPDECARB-RXN
Reactome:R-HSA-73564 "UMPS dimer decarboxylates OMP to UMP"
RHEA:11596