FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term protein-N-terminal amino-acid acetyltransferase activity ID (Ontology) GO:0004596 (Gene Ontology)
Definition Catalysis of the reaction: acetyl-CoA + an N-terminal L-alpha-aminoacyl-[protein] = CoA + H+ + N-terminal Nalpha-acetyl-L-alpha-aminoacyl-[protein].[ PubMed:30054468 ]
Also Known As "acetyl-CoA:peptide alpha-N-acetyltransferase activity" ; "acetyl-CoA:peptide nalpha-acetyltransferase activity" ; "nalpha-acetyltransferase activity" (for all, see Synonyms field below)
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      10
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 protein-N-terminal amino-acid acetyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       7     10
     enables | protein-N-terminal amino-acid acetyltransferase activity       --      10
Spanning Tree (Parents/Children)
Only view relationship: 
N-acetyltransferase activity________
protein N-acyltransferase activity__|
                                    protein N-acetyltransferase activity
                                     |__protein-N-terminal amino-acid acetyltransferase activity  18 rec.
                                         |__protein N-terminal-methionine acetyltransferase activity
                                         |__protein N-terminal-serine acetyltransferase activity 2 rec.
                                         |__protein-N-terminal-alanine acetyltransferase activity
                                         |__protein-N-terminal-glutamate acetyltransferase activity 1 rec.
                                         |__tubulin N-terminal-methionine acetyltransferase activity 1 rec.
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Is a protein N-acetyltransferase activity
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Synonyms
  • "acetyl-CoA:peptide alpha-N-acetyltransferase activity" EXACT
    "acetyl-CoA:peptide nalpha-acetyltransferase activity" EXACT
    "amino-terminal amino acid-acetylating enzyme activity" RELATED
    "beta-endorphin acetyltransferase activity" NARROW
    "N(alpha)-acetyltransferase activity" RELATED
    "nalpha-acetyltransferase activity" EXACT
    "NAT activity" RELATED
    "peptide acetyltransferase activity" RELATED
    "peptide alpha-N-acetyltransferase activity" EXACT
    "protein N-terminal acetyltransferase activity" EXACT
Secondary IDs
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EC:2.3.1.255
Reactome:R-HSA-6814090 "NatC acetylates ARFFRP1"
RHEA:21028