FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term phosphogluconate dehydrogenase (decarboxylating) activity ID (Ontology) GO:0004616 (Gene Ontology)
Definition Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.[ EC:1 ]
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 phosphogluconate dehydrogenase (decarboxylating) activity (all annotations which use CV term, excluding "NOT" statements)
     enables | phosphogluconate dehydrogenase (decarboxylating) activity
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  oxidoreductase activity, acting on CH-OH group of donors
   |__oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
       |__phosphogluconate dehydrogenase (decarboxylating) activity  1 rec.
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Is a oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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Synonyms
  • "6-phospho-D-gluconate dehydrogenase activity" RELATED[ EC:1 ]
    "6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating)" RELATED[ EC:1 ]
    "6-phosphogluconate dehydrogenase (decarboxylating)" RELATED[ EC:1 ]
    "6-phosphogluconic carboxylase activity" RELATED[ EC:1 ]
    "6-phosphogluconic dehydrogenase activity" BROAD[ EC:1 ]
    "6PGD activity" RELATED[ EC:1 ]
    "phosphogluconic acid dehydrogenase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.1.1.44
MetaCyc:RXN-9952
Reactome:R-HSA-71299 "PGD decarboxylates 6-phospho-D-gluconate"
RHEA:10116