FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term phosphatidylcholine lysophospholipase A1 activity ID (Ontology) GO:0004622 (Gene Ontology)
Definition Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphocholine + H2O = a fatty acid + H+ + sn-glycerol 3-phosphocholine.
Also Known As"phosphatidylcholine lysophospholipase A1-type activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 phosphatidylcholine lysophospholipase A1 activity (all annotations which use CV term, excluding "NOT" statements)
     enables | phosphatidylcholine lysophospholipase A1 activity
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  A1-type glycerophospholipase activity
   |__lysophospholipase A1 activity
       |__phosphatidylcholine lysophospholipase A1 activity  5 rec.
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Is a lysophospholipase A1 activity
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Synonyms
  • "2-lysophosphatidylcholine acylhydrolase activity" RELATED[ EC:3 ]
    "lecithinase B activity" RELATED[ EC:3 ]
    "lecitholipase activity" RELATED[ EC:3 ]
    "lysolecithinase activity" RELATED[ EC:3 ]
    "lysophopholipase L2" RELATED[ EC:3 ]
    "lysophosphatidase activity" RELATED[ EC:3 ]
    "lysophosphatidylcholine hydrolase activity" RELATED[ EC:3 ]
    "lysophospholipase A1" RELATED[ EC:3 ]
    "lysophospholipase activity" BROAD[ EC:3 ]
    "phosphatidase B" RELATED[ EC:3 ]
    "phosphatidylcholine lysophospholipase A1-type activity" EXACT
    "phospholipase B activity" RELATED[ EC:3 ]
Secondary IDs
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EC:3.1.1.5
MetaCyc:LYSOPHOSPHOLIPASE-RXN
Reactome:R-HSA-1482545 "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C"
Reactome:R-HSA-1482571 "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C"
Reactome:R-HSA-1482612 "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]"
Reactome:R-HSA-1482629 "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C"
Reactome:R-HSA-1482685 "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]"
Reactome:R-HSA-1482696 "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C"
Reactome:R-HSA-6814254 "PNPLA6 hydrolyzes LysoPtdCho"
Reactome:R-HSA-6814766 "GDPD1 hydrolyzes LysoPtdCho"
Reactome:R-HSA-6814778 "GDPD3 hydrolyzes LysoPtdCho"
Reactome:R-HSA-8847912 "PNPLA7 hydrolyzes LysoPtdCho"
RHEA:15177