FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term D-type glycerophospholipase activity ID (Ontology) GO:0004630 (Gene Ontology)
Definition A glycerophospholipase activity that cleaves the second phosphodiester bond between the phosphate and phospholipid, releasing a phosphatidic acid.[ PubMed:30109646 ]
Also Known As "D-type phospholipase activity" ; "phospholipase D activity"
Comment
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 D-type glycerophospholipase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | D-type glycerophospholipase activity       1
Spanning Tree (Parents/Children)
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phosphoric ester hydrolase activity
 |__phosphoric diester hydrolase activity__
phospholipase activity                     |
 |__glycerophospholipase activity__________|
                                           D-type glycerophospholipase activity  2 rec.
                                            |__cardiolipin phospholipase D activity 1 rec.
                                            |__glycosylphosphatidylinositol phospholipase D activity
                                            |__GPI anchor phospholipase D activity
                                            |__N-acylphosphatidylethanolamine-specific phospholipase D activity
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Is a glycerophospholipase activity
phosphoric diester hydrolase activity
Part of
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Synonyms
  • "choline phosphatase activity" RELATED[ EC:3 ]
    "D-type phospholipase activity" EXACT
    "lecithinase D activity" RELATED[ EC:3 ]
    "lipophosphodiesterase II activity" RELATED[ EC:3 ]
    "phosphatidylcholine phosphatidohydrolase activity" RELATED[ EC:3 ]
    "phospholipase D activity" EXACT
Secondary IDs
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EC:3.1.4.4
MetaCyc:PHOSCHOL-RXN
Reactome:R-HSA-1483142 "PC is transphosphatidylated to PG by PLD1-4/6"
Reactome:R-HSA-1483182 "PC is hydrolyzed to PA and choline by PLD1/2"
Reactome:R-HSA-2029471 "Hydrolysis of PC to PA by PLD"
RHEA:14445
RHEA:41412
RHEA:41416