FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term phosphopantothenate--cysteine ligase activity ID (Ontology) GO:0004632 (Gene Ontology)
Definition Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives.[ EC:6 ]
Also Known As"phosphopantothenate-cysteine ligase activity" ; "phosphopantothenoylcysteine synthetase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 phosphopantothenate--cysteine ligase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | phosphopantothenate--cysteine ligase activity
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  ligase activity, forming carbon-nitrogen bonds
   |__acid-amino acid ligase activity
       |__phosphopantothenate--cysteine ligase activity  1 rec.
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Is a acid-amino acid ligase activity
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Synonyms
  • "(R)-4'-phosphopantothenate:L-cysteine ligase activity" RELATED[ EC:6 ]
    "phosphopantothenate-cysteine ligase activity" EXACT
    "phosphopantothenoylcysteine synthetase activity" EXACT
Secondary IDs
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EC:6.3.2.5
MetaCyc:P-PANTOCYSLIG-RXN
Reactome:R-HSA-196753 "2xPPCS ligates PPanK with Cys"
RHEA:19397