FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term phosphoribosylamine-glycine ligase activity ID (Ontology) GO:0004637 (Gene Ontology)
Definition Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H+ + phosphate.[ EC:6 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 phosphoribosylamine-glycine ligase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | phosphoribosylamine-glycine ligase activity
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  ligase activity
   |__ligase activity, forming carbon-nitrogen bonds
       |__phosphoribosylamine-glycine ligase activity  1 rec.
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Is a ligase activity, forming carbon-nitrogen bonds
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Synonyms
  • "2-amino-N-ribosylacetamide 5'-phosphate kinosynthase activity" RELATED[ EC:6 ]
    "5'-phosphoribosylglycinamide synthetase activity" RELATED[ EC:6 ]
    "5-phospho-D-ribosylamine:glycine ligase (ADP-forming)" RELATED[ EC:6 ]
    "GAR" RELATED[ EC:6 ]
    "GAR synthetase activity" RELATED[ EC:6 ]
    "GARS activity" RELATED[ EC:6 ]
    "glycinamide ribonucleotide synthetase activity" RELATED[ EC:6 ]
    "glycineamide ribonucleotide synthetase activity" RELATED[ EC:6 ]
    "phosphoribosylglycinamide synthetase activity" RELATED[ EC:6 ]
    "phosphoribosylglycineamide synthetase activity" RELATED[ EC:6 ]
Secondary IDs
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EC:6.3.4.13
KEGG_REACTION:R04144
MetaCyc:GLYRIBONUCSYN-RXN
Reactome:R-HSA-73814 "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi"
RHEA:17453