FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term poly(ADP-ribose) glycohydrolase activity ID (Ontology) GO:0004649 (Gene Ontology)
Definition Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.[ EC:3 ]
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 poly(ADP-ribose) glycohydrolase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | poly(ADP-ribose) glycohydrolase activity
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  hydrolase activity, acting on glycosyl bonds
   |__hydrolase activity, hydrolyzing O-glycosyl compounds
       |__poly(ADP-ribose) glycohydrolase activity  1 rec.
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Is a hydrolase activity, hydrolyzing O-glycosyl compounds
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EC:3.2.1.143
MetaCyc:3.2.1.143-RXN
Reactome:R-HSA-5651828 "PARG dePARylates PARP1,PARP2"
Reactome:R-HSA-8952903 "ADPRHL2 hydrolyses poly(ADP-ribose)"
RHEA:52216