FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term protein farnesyltransferase activity ID (Ontology) GO:0004660 (Gene Ontology)
Definition Catalysis of the reaction: L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate.[ PubMed:8621375 ]
Also Known As "protein-cysteine farnesyltransferase activity"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Genes
 protein farnesyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       2
     contributes_to | protein farnesyltransferase activity       2
Spanning Tree (Parents/Children)
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prenyltransferase activity_______________
catalytic activity, acting on a protein__|
                                         protein prenyltransferase activity
                                          |__protein farnesyltransferase activity  2 rec.
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Is a protein prenyltransferase activity
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Synonyms
  • "CAAX farnesyltransferase activity" NARROW[ EC:2 ]
    "farnesyl-diphosphate:protein-cysteine farnesyltransferase activity" RELATED[ EC:2 ]
    "FTase activity" RELATED[ EC:2 ]
    "protein-cysteine farnesyltransferase activity" EXACT
Secondary IDs
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EC:2.5.1.58
MetaCyc:RXN-17573
Reactome:R-HSA-2530501 "FNTA:FNTB transfers FARN to GNGT1"
Reactome:R-HSA-9647978 "pro-RAS proteins are farnesylated"
Reactome:R-HSA-9948016 "FNTA:FNTB transfers farnesyl to GBP1"
RHEA:13345