FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term prostaglandin-D synthase activity ID (Ontology) GO:0004667 (Gene Ontology)
Definition Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).[ EC:5 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 prostaglandin-D synthase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | prostaglandin-D synthase activity
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  isomerase activity
   |__intramolecular oxidoreductase activity
       |__prostaglandin-D synthase activity  1 rec.
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Is a intramolecular oxidoreductase activity
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Synonyms
  • "(5,13)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase activity" RELATED[ EC:5 ]
    "PGD2 synthase activity" RELATED[ EC:5 ]
    "PGH-PGD isomerase activity" RELATED[ EC:5 ]
    "prostaglandin D2 synthase activity" RELATED[ EC:5 ]
    "prostaglandin-H2 D-isomerase activity" RELATED[ EC:5 ]
    "prostaglandin-R-prostaglandin D isomerase activity" RELATED[ EC:5 ]
Secondary IDs
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EC:5.3.99.2
KEGG_REACTION:R02266
MetaCyc:PROSTAGLANDIN-D-SYNTHASE-RXN
Reactome:R-HSA-2161620 "PGH2 is isomerised to PGD2 by PTGDS"
Reactome:R-HSA-2161701 "PGH2 is isomerised to PGD2 by HPGDS"
RHEA:10600