FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term AMP-activated protein kinase activity ID (Ontology) GO:0004679 (Gene Ontology)
Definition Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP.
Also Known As"5'-AMP-activated protein kinase activity" ; "protein kinase A activity"
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Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 AMP-activated protein kinase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | AMP-activated protein kinase activity       --
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  protein kinase activity
   |__protein serine/threonine kinase activity
       |__AMP-activated protein kinase activity  2 rec.
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Is a protein serine/threonine kinase activity
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Synonyms
  • "5'-AMP-activated protein kinase activity" EXACT
    "AMPK activity" RELATED
    "protein kinase A activity" EXACT
    "SNF1A/AMP-activated protein kinase activity" NARROW
Secondary IDs
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Reactome:R-HSA-1592244 "AMPK phosphorylates PPARGC1A"
Reactome:R-HSA-163691 "Phosphorylation of ChREBP at Serine 556 by AMPK"
Reactome:R-HSA-200423 "pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis"
Reactome:R-HSA-380927 "p-AMPK phosphorylates TSC1:TSC2"
Reactome:R-HSA-447074 "AMPK phosphorylates Raptor in the mTORC1 complex"
Reactome:R-HSA-5673768 "p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex"
Reactome:R-HSA-6805470 "AMPK phosphorylates TP53"