FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
Help Close All Open All
General Information
Term cAMP-dependent protein kinase activity ID (Ontology) GO:0004691 (Gene Ontology)
Definition cAMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.[ PubMed:32935175 PubMed:35053423 PubMed:35805104 ]
Also Known As "3',5' cAMP-dependent protein kinase activity" ; "3',5'-cAMP-dependent protein kinase activity" ; "adenosine 3',5'-cyclophosphate-dependent protein kinase activity" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       4
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 cAMP-dependent protein kinase activity (all annotations which use CV term, excluding "NOT" statements)       1      4
     enables | cAMP-dependent protein kinase activity       --       4
Spanning Tree (Parents/Children)
Only view relationship: 
  protein serine/threonine kinase activity
   |__cyclic nucleotide-dependent protein kinase activity
       |__cAMP-dependent protein kinase activity  5 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a cyclic nucleotide-dependent protein kinase activity
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "3',5' cAMP-dependent protein kinase activity" EXACT
    "3',5'-cAMP-dependent protein kinase activity" EXACT
    "adenosine 3',5'-cyclophosphate-dependent protein kinase activity" EXACT
    "AMPK" RELATED[ EC:2 ]
    "ATP:protein phosphotransferase (cAMP-dependent) activity" RELATED[ EC:2 ]
    "cAMP-dependent protein kinase, intrinsic catalyst activity" EXACT
    "cyclic AMP-dependent protein kinase activity" EXACT
    "PKA" RELATED[ EC:2 ]
    "PKA C" RELATED[ EC:2 ]
    "protein kinase A activity" BROAD[ EC:2 ]
    "STK22" RELATED[ EC:2 ]
Secondary IDs
hide External Crossreferences & Linkouts
EC:2.7.11.11
Reactome:R-HSA-163672 "Phosphorylation of ChREBP at Thr(653) by PKA"
Reactome:R-HSA-163676 "Phosphorylation of pChREBP (Thr 653) at Ser(196) by PKA"
Reactome:R-HSA-163773 "PKA tetramer:cAMP phosphorylates PF2K-Pase"
Reactome:R-HSA-177275 "PKA phosphorylates DARPP-32 on Thr34"
Reactome:R-HSA-177284 "PKA phosphorylates PDE4B"
Reactome:R-HSA-432232 "Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA)"
Reactome:R-HSA-5610717 "PKA phosphorylates GLI2"
Reactome:R-HSA-5610720 "PKA phosphorylates GLI3"
Reactome:R-HSA-5610741 "PKA phosphorylates GLI1"
Reactome:R-HSA-5617179 "PRKACA phosphorylates TNNI3"
Reactome:R-HSA-5617182 "PRKACA phosphorylates PLN"
Reactome:R-HSA-5687088 "PKA phosphorylates MAPKAPK5"
Reactome:R-HSA-913451 "IL3RB is phosphorylated on Ser-585"
Reactome:R-HSA-9838321 "PRKACA phosphorylates TFAM in the mitochondrial matrix"
Reactome:R-HSA-9861318 "PKA phosphorylates NOS3 (eNOS) on serine-633"