FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term diacylglycerol-dependent serine/threonine kinase activity ID (Ontology) GO:0004697 (Gene Ontology)
Definition Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.[ EC:2 ]
Also Known As"diacylglycerol-activated phospholipid-dependent PKC activity" ; "diacylglycerol-activated phospholipid-dependent protein kinase C activity" ; "PKC activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 diacylglycerol-dependent serine/threonine kinase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | diacylglycerol-dependent serine/threonine kinase activity
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  protein kinase activity
   |__protein serine/threonine kinase activity
       |__diacylglycerol-dependent serine/threonine kinase activity  6 rec.
           |__calcium,diacylglycerol-dependent serine/threonine kinase activity 3 rec.
           |__diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3 rec.
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Is a protein serine/threonine kinase activity
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Synonyms
  • "ATP:protein phosphotransferase (diacylglycerol-dependent) activity" RELATED[ EC:2 ]
    "cPKC" RELATED[ EC:2 ]
    "cPKCalpha" RELATED[ EC:2 ]
    "cPKCbeta" RELATED[ EC:2 ]
    "cPKCgamma" RELATED[ EC:2 ]
    "diacylglycerol-activated phospholipid-dependent PKC activity" EXACT
    "diacylglycerol-activated phospholipid-dependent protein kinase C activity" EXACT
    "nPKC" RELATED[ EC:2 ]
    "nPKCdelta" RELATED[ EC:2 ]
    "nPKCepsilon" RELATED[ EC:2 ]
    "nPKCeta" RELATED[ EC:2 ]
    "nPKCtheta" RELATED[ EC:2 ]
    "PKC" RELATED[ EC:2 ]
    "PKC activity" EXACT
    "Pkc1p" RELATED[ EC:2 ]
    "PKCalpha" RELATED[ EC:2 ]
    "PKCbeta" RELATED[ EC:2 ]
    "PKCdelta" RELATED[ EC:2 ]
    "PKCepsilon" RELATED[ EC:2 ]
    "PKCgamma" RELATED[ EC:2 ]
    "protein kinase Cepsilon activity" NARROW[ EC:2 ]
    "STK24" RELATED[ EC:2 ]
Secondary IDs
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EC:2.7.11.13
Reactome:R-HSA-5218805 "PKC autophosphorylates"
Reactome:R-HSA-751040 "PKC phosphorylates G alpha (z)"
Reactome:R-HSA-9626817 "PKC phosphorylates NCF1"