FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term diacylglycerol-dependent, calcium-independent serine/threonine kinase activity ID (Ontology) GO:0004699 (Gene Ontology)
Definition Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction is activated by diacylglycerol but not by calcium.[ PubMed:34834162 ]
Also Known As"calcium-independent PKC activity" ; "novel protein kinase C activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | diacylglycerol-dependent, calcium-independent serine/threonine kinase activity       --
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  protein serine/threonine kinase activity
   |__diacylglycerol-dependent serine/threonine kinase activity
       |__diacylglycerol-dependent, calcium-independent serine/threonine kinase activity  3 rec.
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Is a diacylglycerol-dependent serine/threonine kinase activity
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Synonyms
  • "atypical protein kinase C activity" RELATED
    "calcium-independent PKC activity" EXACT
    "novel protein kinase C activity" EXACT[ PubMed:9601053 ]
Secondary IDs
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Reactome:R-HSA-198314 "DAG stimulates protein kinase C-delta"
Reactome:R-HSA-2730863 "Phosphorylation of CARMA1 by PKC-theta"
Reactome:R-HSA-374664 "Phosphorylation and activation of Ezrin"
Reactome:R-HSA-429698 "PRKD1,2,3 phosphorylates CERT1-2"
Reactome:R-HSA-450533 "PKCdelta phosphorylates HuR"
Reactome:R-HSA-5607740 "PKC-delta phosphorylates CARD9"
Reactome:R-HSA-8932284 "PKC phosphorylates NFE2L2"
Reactome:R-HSA-909552 "Phosphorylation of STAT1 at Ser727"