FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term non-membrane spanning protein tyrosine phosphatase activity ID (Ontology) GO:0004726 (Gene Ontology)
Definition Catalysis of the reaction: non-membrane spanning protein tyrosine phosphate + H2O = non-membrane spanning protein tyrosine + phosphate.[ PubMed:34353440 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       8
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Relevant FlyBase reports
 Gene Groups Genes
 non-membrane spanning protein tyrosine phosphatase activity (all annotations which use CV term, excluding "NOT" statements)       1      8
     enables | non-membrane spanning protein tyrosine phosphatase activity       --       8
 NOT | enables | non-membrane spanning protein tyrosine phosphatase activity       --       2
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  phosphoprotein phosphatase activity
   |__protein tyrosine phosphatase activity
       |__non-membrane spanning protein tyrosine phosphatase activity  9 rec.
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Reactome:R-HSA-177923 "Sustained activation of SRC kinase by SHP2"
Reactome:R-HSA-177924 "Dephosphorylation of Gab1 by SHP2"
Reactome:R-HSA-177926 "Dephosphorylation of PAG by SHP2"
Reactome:R-HSA-177935 "SHP2 dephosphorylates Tyr 992 on EGFR"
Reactome:R-HSA-9635739 "PTPN7 dephosphorylates p-T,Y-MAPKs"