FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
Help Close All Open All
General Information
Term ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ID (Ontology) GO:0004748 (Gene Ontology)
Definition Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.[ EC:1 ]
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (all annotations which use CV term, excluding "NOT" statements)       2
     enables | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor       2
Spanning Tree (Parents/Children)
Only view relationship: 
  oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor
   |__ribonucleoside-diphosphate reductase activity
       |__ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor  2 rec.
           |__ADP reductase activity
           |__CDP reductase activity
           |__UDP reductase activity
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a ribonucleoside-diphosphate reductase activity
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase activity" RELATED[ EC:1 ]
    "2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase activity" RELATED[ EC:1 ]
Secondary IDs
hide External Crossreferences & Linkouts
EC:1.17.4.1
MetaCyc:RIBONUCLEOSIDE-DIP-REDUCTI-RXN
Reactome:R-HSA-111751 "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)"
Reactome:R-HSA-111804 "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)"
RHEA:23252