FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term steroid Delta-isomerase activity ID (Ontology) GO:0004769 (Gene Ontology)
Definition Catalysis of the reaction: a 3-oxo-delta(5)-steroid = a 3-oxo-delta(4)-steroid.
Also Known As "steroid D-isomerase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 steroid Delta-isomerase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | steroid Delta-isomerase activity
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  intramolecular oxidoreductase activity
   |__intramolecular oxidoreductase activity, transposing C=C bonds
       |__steroid Delta-isomerase activity  2 rec.
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Is a intramolecular oxidoreductase activity, transposing C=C bonds
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Synonyms
  • "3-oxosteroid delta5-delta4-isomerase activity" RELATED[ EC:5 ]
    "3-oxosteroid isomerase activity" RELATED[ EC:5 ]
    "delta(5)-3-keto steroid isomerase activity" RELATED[ EC:5 ]
    "delta(5)-3-ketosteroid isomerase activity" RELATED[ EC:5 ]
    "delta(5)-3-oxosteroid isomerase activity" RELATED[ EC:5 ]
    "delta(5)-steroid isomerase activity" RELATED[ EC:5 ]
    "delta5(or delta4)-3-keto steroid isomerase activity" RELATED[ EC:5 ]
    "delta5-3-keto steroid isomerase activity" RELATED[ EC:5 ]
    "delta5-3-ketosteroid isomerase activity" RELATED[ EC:5 ]
    "delta5-3-oxosteroid isomerase activity" RELATED[ EC:5 ]
    "delta5-ketosteroid isomerase activity" RELATED[ EC:5 ]
    "delta5-steroid isomerase activity" RELATED[ EC:5 ]
    "hydroxysteroid isomerase activity" RELATED[ EC:5 ]
    "steroid D-isomerase activity" EXACT
    "steroid isomerase activity" RELATED[ EC:5 ]
Secondary IDs
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EC:5.3.3.1
MetaCyc:STEROID-DELTA-ISOMERASE-RXN
Reactome:R-HSA-193052 "Pregn-5-ene-3,20-dione isomerizes to progesterone"
Reactome:R-HSA-193073 "HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST"
Reactome:R-HSA-193961 "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone"
Reactome:R-HSA-195690 "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol"
Reactome:R-HSA-6807052 "EBP isomerizes ZYMSTNL to LTHSOL"
RHEA:14709
RHEA:32187
RHEA:43928
RHEA:43936
RHEA:56936