FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term sterol ester esterase activity ID (Ontology) GO:0004771 (Gene Ontology)
Definition Catalysis of the reaction: a sterol ester + H2O = a fatty acid + a sterol + H+.
Also Known As"sterol esterase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 sterol ester esterase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | sterol ester esterase activity
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hydrolase activity, acting on ester bonds
 |__lipase activity______________________
 |__carboxylic ester hydrolase activity__|
                                         sterol ester esterase activity  2 rec.
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Is a lipase activity
carboxylic ester hydrolase activity
Part of
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Synonyms
  • "acylcholesterol lipase activity" RELATED[ EC:3 ]
    "cholesterase activity" RELATED[ EC:3 ]
    "cholesterol ester hydrolase activity" RELATED[ EC:3 ]
    "cholesterol ester synthase activity" NARROW[ EC:3 ]
    "cholesterol esterase activity" NARROW[ EC:3 ]
    "cholesteryl ester hydrolase activity" RELATED[ EC:3 ]
    "cholesteryl ester synthase activity" RELATED[ EC:3 ]
    "cholesteryl esterase activity" RELATED[ EC:3 ]
    "sterol ester hydrolase activity" RELATED[ EC:3 ]
    "sterol esterase activity" EXACT
    "steryl-ester acylhydrolase activity" RELATED[ EC:3 ]
    "triterpenol esterase activity" RELATED[ EC:3 ]
Secondary IDs
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EC:3.1.1.13
MetaCyc:STEROL-ESTERASE-RXN
Reactome:R-HSA-192417 "Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase)"
Reactome:R-HSA-6813720 "NCEH1 hydrolyzes cholesterol esters"
Reactome:R-HSA-8865667 "LIPA hydrolyses sterol esters to sterols and fatty acids"
RHEA:10100
RHEA:33543
RHEA:33547
RHEA:33875
RHEA:36403