FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term succinate-semialdehyde dehydrogenase (NAD+) activity ID (Ontology) GO:0004777 (Gene Ontology)
Definition Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 succinate-semialdehyde dehydrogenase (NAD+) activity (all annotations which use CV term, excluding "NOT" statements)
     enables | succinate-semialdehyde dehydrogenase (NAD+) activity
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aldehyde dehydrogenase [NAD(P)+] activity
 |__aldehyde dehydrogenase (NAD+) activity_______________________________________________________
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor  |
 |__succinate-semialdehyde dehydrogenase [NAD(P)+] activity______________________________________|
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Is a aldehyde dehydrogenase (NAD+) activity
succinate-semialdehyde dehydrogenase [NAD(P)+] activity
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Synonyms
  • "succinate semialdehyde dehydrogenase activity" BROAD[ EC:1 ]
    "succinate semialdehyde:NAD+ oxidoreductase activity" RELATED[ EC:1 ]
    "succinate-semialdehyde dehydrogenase activity" BROAD
    "succinate-semialdehyde:NAD+ oxidoreductase activity" RELATED[ EC:1 ]
    "succinic semialdehyde dehydrogenase activity" BROAD[ EC:1 ]
    "succinyl semialdehyde dehydrogenase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.2.1.24
MetaCyc:SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN
Reactome:R-HSA-888548 "ALDH5A1 dehydrogenates SUCCSA to SUCCA"
RHEA:13217