FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term triacylglycerol lipase activity ID (Ontology) GO:0004806 (Gene Ontology)
Definition Catalysis of the reaction: a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H+.
Also Known As "TAG activity" ; "triglyceride lipase activity"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      54
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 triacylglycerol lipase activity (all annotations which use CV term, excluding "NOT" statements)       4     54
     enables | triacylglycerol lipase activity       --      54
 NOT | enables | triacylglycerol lipase activity       --       1
Spanning Tree (Parents/Children)
Only view relationship: 
hydrolase activity, acting on ester bonds
 |__lipase activity______________________
 |__carboxylic ester hydrolase activity__|
                                         triacylglycerol lipase activity  59 rec.
                                          |__lipoprotein lipase activity 1 rec.
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Is a lipase activity
carboxylic ester hydrolase activity
Part of
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Synonyms
  • "amano AP" RELATED[ EC:3 ]
    "amano B" RELATED[ EC:3 ]
    "amano CE" RELATED[ EC:3 ]
    "amano CES" RELATED[ EC:3 ]
    "amano P" RELATED[ EC:3 ]
    "amno N-AP" RELATED[ EC:3 ]
    "butyrinase activity" RELATED[ EC:3 ]
    "cacordase activity" RELATED[ EC:3 ]
    "capalase L" RELATED[ EC:3 ]
    "GA 56" RELATED[ EC:3 ]
    "GEH" RELATED[ EC:3 ]
    "glycerol ester hydrolase activity" RELATED[ EC:3 ]
    "glycerol-ester hydrolase activity" RELATED[ EC:3 ]
    "heparin releasable hepatic lipase" NARROW[ EC:3 ]
    "hepatic lipase" NARROW[ EC:3 ]
    "hepatic monoacylglycerol acyltransferase" NARROW[ EC:3 ]
    "lipazin" RELATED[ EC:3 ]
    "liver lipase" NARROW[ EC:3 ]
    "meito MY 30" RELATED[ EC:3 ]
    "meito sangyo OF lipase" RELATED[ EC:3 ]
    "post-heparin plasma protamine-resistant lipase" NARROW[ EC:3 ]
    "PPL" RELATED[ EC:3 ]
    "salt-resistant post-heparin lipase" NARROW[ EC:3 ]
    "steapsin" RELATED[ EC:3 ]
    "TAG activity" EXACT[ PubMed:16054079 ]
    "takedo 1969-4-9" RELATED[ EC:3 ]
    "triacetinase activity" RELATED[ EC:3 ]
    "triacylglycerol acylhydrolase activity" RELATED[ EC:3 ]
    "triacylglycerol ester hydrolase activity" RELATED[ EC:3 ]
    "tributyrase activity" RELATED[ EC:3 ]
    "tributyrin esterase activity" RELATED[ EC:3 ]
    "tributyrinase activity" RELATED[ EC:3 ]
    "triglyceridase activity" RELATED[ EC:3 ]
    "triglyceride hydrolase activity" RELATED[ EC:3 ]
    "triglyceride lipase activity" EXACT
    "triolein hydrolase activity" RELATED[ EC:3 ]
    "tween hydrolase activity" RELATED[ EC:3 ]
    "tween-hydrolyzing esterase activity" RELATED[ EC:3 ]
    "tweenase activity" RELATED[ EC:3 ]
    "tweenesterase activity" RELATED[ EC:3 ]
Secondary IDs
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EC:3.1.1.3
MetaCyc:RXN-19278
Reactome:R-HSA-1482777 "TAG is hydrolyzed to DAG by PNPLA2/3"
Reactome:R-HSA-163551 "triacylglycerol + H2O -> diacylglycerol + fatty acid"
Reactome:R-HSA-5694109 "LIPC dimer hydrolyses TAG to DAG and FA"
Reactome:R-HSA-8848338 "PNPLA4 hydrolyzes TAG"
Reactome:R-HSA-8848339 "PNPLA5 hydrolyzes TAG"
RHEA:12044