FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term alanine-tRNA ligase activity ID (Ontology) GO:0004813 (Gene Ontology)
Definition Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).[ EC:6 ]
Also Known As"alanyl-tRNA synthetase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 alanine-tRNA ligase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | alanine-tRNA ligase activity
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ligase activity, forming carbon-oxygen bonds__
catalytic activity, acting on a tRNA__________|
                                              aminoacyl-tRNA ligase activity
                                               |__alanine-tRNA ligase activity  3 rec.
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Is a aminoacyl-tRNA ligase activity
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Synonyms
  • "Ala-tRNA synthetase activity" RELATED[ EC:6 ]
    "alanine transfer RNA synthetase activity" RELATED[ EC:6 ]
    "alanine translase activity" RELATED[ EC:6 ]
    "alanine tRNA synthetase activity" RELATED[ EC:6 ]
    "alanine-transfer RNA ligase activity" RELATED[ EC:6 ]
    "alanyl-transfer ribonucleate synthase activity" RELATED[ EC:6 ]
    "alanyl-transfer ribonucleate synthetase activity" RELATED[ EC:6 ]
    "alanyl-transfer ribonucleic acid synthetase activity" RELATED[ EC:6 ]
    "alanyl-transfer RNA synthetase activity" RELATED[ EC:6 ]
    "alanyl-tRNA synthetase activity" EXACT
    "AlaRS" RELATED[ EC:6 ]
    "L-alanine:tRNAAla ligase (AMP-forming)" RELATED[ EC:6 ]
Secondary IDs
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EC:6.1.1.7
MetaCyc:ALANINE--TRNA-LIGASE-RXN
Reactome:R-HSA-379864 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate"
Reactome:R-HSA-380177 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate"
RHEA:12540