FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term cysteine-tRNA ligase activity ID (Ontology) GO:0004817 (Gene Ontology)
Definition Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).[ EC:6 ]
Also Known As"cysteinyl-tRNA synthetase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 cysteine-tRNA ligase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | cysteine-tRNA ligase activity
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ligase activity, forming carbon-oxygen bonds__
catalytic activity, acting on a tRNA__________|
                                              aminoacyl-tRNA ligase activity
                                               |__cysteine-tRNA ligase activity  2 rec.
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Is a aminoacyl-tRNA ligase activity
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Synonyms
  • "cysteine translase activity" RELATED[ EC:6 ]
    "cysteinyl-transfer ribonucleate synthetase activity" RELATED[ EC:6 ]
    "cysteinyl-transferRNA synthetase activity" RELATED[ EC:6 ]
    "cysteinyl-tRNA synthetase activity" EXACT
    "L-cysteine:tRNACys ligase (AMP-forming)" RELATED[ EC:6 ]
Secondary IDs
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EC:6.1.1.16
MetaCyc:CYSTEINE--TRNA-LIGASE-RXN
Reactome:R-HSA-379887 "cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate"
Reactome:R-HSA-380158 "cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate"
RHEA:17773