FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term lysine-tRNA ligase activity ID (Ontology) GO:0004824 (Gene Ontology)
Definition Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).[ EC:6 ]
Also Known As"lysyl-tRNA synthetase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 lysine-tRNA ligase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | lysine-tRNA ligase activity
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ligase activity, forming carbon-oxygen bonds__
catalytic activity, acting on a tRNA__________|
                                              aminoacyl-tRNA ligase activity
                                               |__lysine-tRNA ligase activity  1 rec.
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Is a aminoacyl-tRNA ligase activity
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Synonyms
  • "L-lysine-transfer RNA ligase activity" RELATED[ EC:6 ]
    "L-lysine:tRNALys ligase (AMP-forming)" RELATED[ EC:6 ]
    "lysine translase activity" RELATED[ EC:6 ]
    "lysine-tRNA synthetase activity" RELATED[ EC:6 ]
    "lysyl-transfer ribonucleate synthetase activity" RELATED[ EC:6 ]
    "lysyl-transfer RNA synthetase activity" RELATED[ EC:6 ]
    "lysyl-tRNA synthetase activity" EXACT
Secondary IDs
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EC:6.1.1.6
MetaCyc:LYSINE--TRNA-LIGASE-RXN
Reactome:R-HSA-380008 "lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate"
Reactome:R-HSA-380233 "lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate"
RHEA:20792