FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term phenylalanine-tRNA ligase activity ID (Ontology) GO:0004826 (Gene Ontology)
Definition Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).[ EC:6 ]
Also Known As"phenylalanyl-tRNA synthetase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 phenylalanine-tRNA ligase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | phenylalanine-tRNA ligase activity
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ligase activity, forming carbon-oxygen bonds__
catalytic activity, acting on a tRNA__________|
                                              aminoacyl-tRNA ligase activity
                                               |__phenylalanine-tRNA ligase activity  3 rec.
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Is a aminoacyl-tRNA ligase activity
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Synonyms
  • "L-phenylalanine:tRNAPhe ligase (AMP-forming) activity" RELATED[ EC:6 ]
    "L-phenylalanyl-tRNA synthetase activity" RELATED[ EC:6 ]
    "phenylalanine translase activity" RELATED[ EC:6 ]
    "phenylalanine-tRNA synthetase activity" RELATED[ EC:6 ]
    "phenylalanyl-transfer ribonucleate synthetase activity" RELATED[ EC:6 ]
    "phenylalanyl-transfer RNA ligase activity" RELATED[ EC:6 ]
    "phenylalanyl-transfer RNA synthetase activity" RELATED[ EC:6 ]
    "phenylalanyl-tRNA ligase activity" RELATED[ EC:6 ]
    "phenylalanyl-tRNA synthetase activity" EXACT
Secondary IDs
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EC:6.1.1.20
MetaCyc:PHENYLALANINE--TRNA-LIGASE-RXN
Reactome:R-HSA-379848 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate"
Reactome:R-HSA-380203 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate"
RHEA:19413