FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term tyrosine-tRNA ligase activity ID (Ontology) GO:0004831 (Gene Ontology)
Definition Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H+.[ EC:6 ]
Also Known As "tyrosyl-tRNA synthetase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 tyrosine-tRNA ligase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | tyrosine-tRNA ligase activity
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ligase activity, forming carbon-oxygen bonds__
catalytic activity, acting on a tRNA__________|
                                              aminoacyl-tRNA ligase activity
                                               |__tyrosine-tRNA ligase activity  2 rec.
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Is a aminoacyl-tRNA ligase activity
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Synonyms
  • "L-tyrosine-tRNA(Tyr) ligase (AMP-forming) activity" RELATED[ EC:6 ]
    "L-tyrosine-tRNATyr ligase (AMP-forming)" RELATED[ EC:6 ]
    "L-tyrosine:tRNATyr ligase (AMP-forming)" RELATED[ EC:6 ]
    "tyrosine translase activity" RELATED[ EC:6 ]
    "tyrosine tRNA synthetase activity" RELATED[ EC:6 ]
    "tyrosine-transfer ribonucleate synthetase activity" RELATED[ EC:6 ]
    "tyrosine-transfer RNA ligase activity" RELATED[ EC:6 ]
    "tyrosyl-transfer ribonucleate synthetase activity" RELATED[ EC:6 ]
    "tyrosyl-transfer ribonucleic acid synthetase activity" RELATED[ EC:6 ]
    "tyrosyl-transfer RNA synthetase activity" RELATED[ EC:6 ]
    "tyrosyl-tRNA ligase activity" RELATED[ EC:6 ]
    "tyrosyl-tRNA synthetase activity" EXACT
Secondary IDs
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EC:6.1.1.1
KEGG_REACTION:R02918
MetaCyc:TYROSINE--TRNA-LIGASE-RXN
Reactome:R-HSA-379980 "tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate"
Reactome:R-HSA-380170 "tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate"
RHEA:10220