FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term valine-tRNA ligase activity ID (Ontology) GO:0004832 (Gene Ontology)
Definition Catalysis of the reaction: L-valine + ATP + tRNA(Val) = L-valyl-tRNA(Val) + AMP + diphosphate + 2 H+.[ EC:6 ]
Also Known As"valyl-tRNA synthetase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 valine-tRNA ligase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | valine-tRNA ligase activity
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ligase activity, forming carbon-oxygen bonds__
catalytic activity, acting on a tRNA__________|
                                              aminoacyl-tRNA ligase activity
                                               |__valine-tRNA ligase activity  2 rec.
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Is a aminoacyl-tRNA ligase activity
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Synonyms
  • "L-valine:tRNAVal ligase (AMP-forming)" RELATED[ EC:6 ]
    "valine transfer ribonucleate ligase activity" RELATED[ EC:6 ]
    "valine translase activity" RELATED[ EC:6 ]
    "valyl-transfer ribonucleate synthetase activity" RELATED[ EC:6 ]
    "valyl-transfer ribonucleic acid synthetase activity" RELATED[ EC:6 ]
    "valyl-transfer RNA synthetase activity" RELATED[ EC:6 ]
    "valyl-tRNA synthetase activity" EXACT
Secondary IDs
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EC:6.1.1.9
KEGG_REACTION:R03665
MetaCyc:VALINE--TRNA-LIGASE-RXN
Reactome:R-HSA-380042 "valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate"
Reactome:R-HSA-380199 "valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate"
RHEA:10704