FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term xanthine dehydrogenase activity ID (Ontology) GO:0004854 (Gene Ontology)
Definition Catalysis of the reaction: xanthine + NAD+ + H2O = urate + NADH + H+.[ EC:1 ]
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 xanthine dehydrogenase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | xanthine dehydrogenase activity
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  oxidoreductase activity, acting on CH or CH2 groups
   |__oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor
       |__xanthine dehydrogenase activity  1 rec.
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Is a oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor
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Synonyms
  • "NAD-xanthine dehydrogenase activity" RELATED[ EC:1 ]
    "xanthine oxidoreductase activity" BROAD[ EC:1 ]
    "xanthine-NAD oxidoreductase activity" RELATED[ EC:1 ]
    "xanthine/NAD(+) oxidoreductase activity" RELATED[ EC:1 ]
    "xanthine/NAD+ oxidoreductase activity" RELATED[ EC:1 ]
    "xanthine:NAD+ oxidoreductase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.17.1.4
MetaCyc:RXN0-901
Reactome:R-HSA-9727349 "XDH dehydrogenates xanthine to form urate"
RHEA:16669