FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term NMDA glutamate receptor activity ID (Ontology) GO:0004972 (Gene Ontology)
Definition A cation channel that opens in response to binding by extracellular glutmate, but only if glycine or D-serine is also bound and the membrane is depolarized. Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages.[ PubMed:10049997 PubMed:7790891 ]
Also Known As "N-methyl-D-aspartate selective glutamate receptor activity" ; "NMDA receptor"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 NMDA glutamate receptor activity (all annotations which use CV term, excluding "NOT" statements)       1      2
     contributes_to | NMDA glutamate receptor activity       --       2
     enables | NMDA glutamate receptor activity       --       2
Spanning Tree (Parents/Children)
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monoatomic ion channel activity
 |__voltage-gated monoatomic ion channel activity_____
dicarboxylic acid transmembrane transporter activity  |
 |__glutamate-gated receptor activity_________________|
glutamate receptor activity                           |
 |__glutamate-gated receptor activity_________________|
amino acid transmembrane transporter activity         |
 |__glutamate-gated receptor activity_________________|
transmitter-gated monoatomic ion channel activity     |
 |__glutamate-gated receptor activity_________________|
voltage-gated channel activity                        |
 |__voltage-gated monoatomic ion channel activity_____|
                                                      NMDA glutamate receptor activity  3 rec.
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Is a glutamate-gated receptor activity
voltage-gated monoatomic ion channel activity
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Synonyms
  • "N-methyl-D-aspartate selective glutamate receptor activity" EXACT
    "NMDA receptor" EXACT
Secondary IDs
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Wikipedia:NMDA_receptor