FB2026_03 , released September 17, 2026
CV Term Report
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Term MAP kinase scaffold activity ID (Ontology) GO:0005078 (Gene Ontology)
Definition The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently.[ PubMed:12511654 PubMed:15213240 PubMed:9405336 ]
Also Known As"MAP-kinase scaffold protein activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 MAP kinase scaffold activity (all annotations which use CV term, excluding "NOT" statements)
     enables | MAP kinase scaffold activity
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structural molecule activity
 |__protein complex scaffold activity___
protein-macromolecule adaptor activity  |
 |__signaling adaptor activity__________|
                                        MAP kinase scaffold activity  6 rec.
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Is a signaling adaptor activity
protein complex scaffold activity
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  • "MAP-kinase scaffold protein activity" EXACT
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