FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term signaling receptor binding ID (Ontology) GO:0005102 (Gene Ontology)
Definition Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.[ ISBN:0198506732 ]
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      40
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 signaling receptor binding (all annotations which use CV term, excluding "NOT" statements)       1     40
     enables | signaling receptor binding       --      40
Spanning Tree (Parents/Children)
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  binding
   |__protein binding
       |__signaling receptor binding  234 rec.
           |__acetylcholine receptor binding 1 rec.
           |__apolipoprotein receptor binding
           |   |__apolipoprotein A-I receptor binding
           |__aryl hydrocarbon receptor binding
           |__benzodiazepine receptor binding
           |__CD4 receptor binding
           |__CD8 receptor binding
           |__CD70 receptor binding
           |__CD154 receptor binding
           |__cytokine receptor binding 16 rec.
           |   |__chemokine receptor binding(+) 1 rec.
           |   |__ciliary neurotrophic factor receptor binding
           |   |__erythropoietin receptor binding
           |   |__granulocyte colony-stimulating factor receptor binding
           |   |__granulocyte macrophage colony-stimulating factor receptor binding
           |   |__growth hormone receptor binding
           |   |__interleukin-1 receptor antagonist activity(+)
           |   |__interleukin-1 receptor binding(+)
           |   |__interleukin-2 receptor binding
           |   |__interleukin-3 receptor binding
           |   |__interleukin-4 receptor binding
           |   |__interleukin-5 receptor binding
           |   |__interleukin-6 receptor binding
           |   |__interleukin-7 receptor binding
           |   |__interleukin-9 receptor binding
           |   |__interleukin-10 receptor binding
           |   |__interleukin-11 receptor binding
           |   |__interleukin-12 receptor binding
           |   |__interleukin-13 receptor binding
           |   |__interleukin-15 receptor binding
           |   |__interleukin-16 receptor binding
           |   |__interleukin-17 receptor binding
           |   |__interleukin-17E receptor binding
           |   |__interleukin-18 receptor binding
           |   |__interleukin-19 receptor binding
           |   |__interleukin-20 receptor binding
           |   |__interleukin-21 receptor binding
           |   |__interleukin-22 receptor binding
           |   |__interleukin-23 receptor binding
           |   |__interleukin-24 receptor binding
           |   |__interleukin-25 receptor binding
           |   |__interleukin-26 receptor binding
           |   |__interleukin-27 receptor binding
           |   |__interleukin-28 receptor binding
           |   |__interleukin-33 receptor binding
           |   |__interleukin-35 receptor binding
           |   |__leukemia inhibitory factor receptor binding
           |   |__macrophage colony-stimulating factor receptor binding
           |   |__neurotrophin receptor binding(+)
           |   |__oncostatin-M receptor binding
           |   |__prolactin receptor binding
           |   |__stem cell factor receptor binding
           |   |__transforming growth factor beta receptor binding(+) 2 rec.
           |   |__tumor necrosis factor receptor superfamily binding(+) 6 rec.
           |   |__type I interferon receptor binding
           |   |__type II interferon receptor binding
           |   |__vascular endothelial growth factor receptor binding(+) 4 rec.
           |__ephrin receptor binding 1 rec.
           |__ErbB-2 class receptor binding
           |__ErbB-3 class receptor binding
           |__ErbB-4 class receptor binding
           |__G protein-coupled receptor binding 59 rec.
           |   |__adenosine receptor binding(+)
           |   |__adrenergic receptor binding(+)
           |   |__adrenomedullin receptor binding
           |   |__alpha-latrotoxin receptor binding
           |   |__angiotensin receptor binding(+)
           |   |__bradykinin receptor binding(+)
           |   |__C5a anaphylatoxin chemotactic receptor binding(+)
           |   |__calcitonin receptor binding
           |   |__cannabinoid receptor binding(+)
           |   |__chemokine receptor binding(+) 1 rec.
           |   |__cysteinyl leukotriene receptor binding(+)
           |   |__dopamine receptor binding(+) 1 rec.
           |   |__endothelial differentiation G protein-coupled receptor binding(+)
           |   |__fMet-Leu-Phe receptor binding
           |   |__follicle-stimulating hormone receptor binding
           |   |__frizzled binding 11 rec.
           |   |__G protein-coupled acetylcholine receptor binding
           |   |__G protein-coupled GABA receptor binding(+)
           |   |__G protein-coupled glutamate receptor binding(+) 1 rec.
           |   |__G protein-coupled histamine receptor binding(+)
           |   |__G protein-coupled nucleotide receptor binding(+)
           |   |__G protein-coupled serotonin receptor binding(+)
           |   |__gastric inhibitory polypeptide receptor binding
           |   |__ghrelin receptor binding
           |   |__glucagon receptor binding
           |   |__leukotriene receptor binding
           |   |__lutropin-choriogonadotropic hormone receptor binding
           |   |__melatonin receptor binding(+)
           |   |__motilin receptor binding
           |   |__neuropeptide receptor binding(+) 12 rec.
           |   |__olfactory receptor binding
           |   |__opioid receptor binding(+)
           |   |__oxytocin receptor binding
           |   |__parathyroid hormone receptor binding(+)
           |   |__platelet activating factor receptor binding
           |   |__prostanoid receptor binding(+)
           |   |__proteinase activated receptor binding(+)
           |   |__secretin receptor binding
           |   |__smoothened binding 4 rec.
           |   |__taste receptor binding(+)
           |   |__thyrotropin-releasing hormone receptor binding
           |   |__urotensin receptor binding
           |   |__vasopressin receptor binding(+)
           |__GABA receptor binding 3 rec.
           |   |__G protein-coupled GABA receptor binding(+)
           |__glutamate receptor binding 2 rec.
           |   |__G protein-coupled glutamate receptor binding(+) 1 rec.
           |   |__ionotropic glutamate receptor binding 1 rec.
           |__growth factor receptor binding 28 rec.
           |   |__epidermal growth factor receptor binding 10 rec.
           |   |__fibroblast growth factor receptor binding(+) 7 rec.
           |   |__glial cell-derived neurotrophic factor receptor binding
           |   |__granulocyte colony-stimulating factor receptor binding
           |   |__granulocyte macrophage colony-stimulating factor receptor binding
           |   |__hepatocyte growth factor receptor binding
           |   |__high molecular weight B cell growth factor receptor binding
           |   |__imaginal disc growth factor receptor binding 7 rec.
           |   |__interleukin-1 receptor binding(+)
           |   |__interleukin-2 receptor binding
           |   |__interleukin-3 receptor binding
           |   |__interleukin-4 receptor binding
           |   |__interleukin-5 receptor binding
           |   |__interleukin-6 receptor binding
           |   |__interleukin-7 receptor binding
           |   |__interleukin-9 receptor binding
           |   |__interleukin-10 receptor binding
           |   |__interleukin-11 receptor binding
           |   |__interleukin-12 receptor binding
           |   |__platelet-derived growth factor receptor binding
           |   |__vascular endothelial growth factor receptor binding(+) 4 rec.
           |__high molecular weight kininogen receptor binding
           |__hormone receptor binding 2 rec.
           |   |__growth hormone receptor binding
           |   |__peptide hormone receptor binding(+) 1 rec.
           |__immunoglobulin receptor binding
           |   |__Fc-gamma receptor I complex binding
           |__insulin receptor binding 15 rec.
           |__insulin-like growth factor receptor binding 1 rec.
           |__integrin binding 13 rec.
           |   |__integrin binding involved in cell-matrix adhesion
           |__intercellular adhesion molecule-3 receptor binding
           |__leptin receptor binding
           |__lipoprotein particle receptor binding 3 rec.
           |   |__high-density lipoprotein particle receptor binding
           |   |__low-density lipoprotein particle receptor binding 1 rec.
           |   |__very-low-density lipoprotein particle receptor binding
           |__MDA-5 binding
           |__MHC protein binding 1 rec.
           |   |__MHC class I protein binding(+)
           |   |__MHC class Ib protein binding(+)
           |   |__MHC class II protein binding(+)
           |__natural killer cell lectin-like receptor binding
           |__netrin receptor binding 1 rec.
           |__neurexin family protein binding 7 rec.
           |__neuroligin family protein binding 1 rec.
           |__neuropilin binding
           |__Notch binding 18 rec.
           |__patched binding 5 rec.
           |__peroxisome proliferator activated receptor binding
           |__RAGE receptor binding
           |__receptor serine/threonine kinase binding 5 rec.
           |   |__transmembrane receptor protein serine/threonine kinase binding(+) 5 rec.
           |__receptor tyrosine kinase binding 11 rec.
           |   |__transmembrane receptor protein tyrosine kinase adaptor activity 5 rec.
           |__receptor tyrosine kinase-like orphan receptor binding
           |__receptor-receptor interaction
           |__RIG-I binding
           |__Roundabout binding 4 rec.
           |__scavenger receptor binding
           |__semaphorin receptor binding 10 rec.
           |__sevenless binding 5 rec.
           |__sulfonylurea receptor binding
           |__T cell receptor binding
           |__Toll binding 8 rec.
           |__Toll-like receptor binding 1 rec.
           |   |__Toll-like receptor 2 binding
           |   |__Toll-like receptor 4 binding
           |__torso binding 3 rec.
           |__transferrin receptor binding
           |__wishful thinking binding
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Is a protein binding
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Synonyms
  • "receptor binding" BROAD
    "receptor ligand" NARROW
    "receptor-associated protein activity" RELATED
Secondary IDs
hide External Crossreferences & Linkouts
Wikipedia:Ligand_(biochemistry)