FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term monoatomic ion channel activity ID (Ontology) GO:0005216 (Gene Ontology)
Definition Enables the facilitated diffusion of a monoatomic ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).[ ISBN:0815340729 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 monoatomic ion channel activity (all annotations which use CV term, excluding "NOT" statements)
     enables | monoatomic ion channel activity       --
 NOT | enables | monoatomic ion channel activity       --
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passive transmembrane transporter activity
 |__channel activity___________________________________
transmembrane transporter activity                     |
 |__monoatomic ion transmembrane transporter activity__|
                                                       monoatomic ion channel activity  467 rec.
                                                        |__ligand-gated monoatomic ion channel activity 297 rec.
                                                        |   |__cyclic nucleotide-activated monoatomic ion channel activity(+) 7 rec.
                                                        |   |__extracellular ligand-gated monoatomic ion channel activity(+) 53 rec.
                                                        |   |__intracellularly ligand-gated monoatomic ion channel activity(+) 15 rec.
                                                        |   |__ionotropic olfactory receptor activity 60 rec.
                                                        |   |__ionotropic taste receptor activity(+) 16 rec.
                                                        |   |__ligand-gated monoatomic anion channel activity(+) 20 rec.
                                                        |   |__ligand-gated monoatomic cation channel activity(+) 94 rec.
                                                        |   |__ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
                                                        |   |__pH-gated monoatomic ion channel activity(+) 10 rec.
                                                        |__light-activated monoatomic ion channel activity
                                                        |   |__light-activated voltage-gated calcium channel activity
                                                        |__mechanosensitive monoatomic ion channel activity 17 rec.
                                                        |   |__cyclic nucleotide-gated mechanosensitive monoatomic ion channel activity
                                                        |   |__mechanosensitive monoatomic cation channel activity(+) 13 rec.
                                                        |__monoatomic anion channel activity 43 rec.
                                                        |   |__chloride channel activity(+) 38 rec.
                                                        |   |__fluoride channel activity
                                                        |   |__iodide channel activity
                                                        |   |__ligand-gated monoatomic anion channel activity(+) 20 rec.
                                                        |   |__voltage-gated monoatomic anion channel activity(+) 8 rec.
                                                        |   |__volume-sensitive anion channel activity(+) 3 rec.
                                                        |__monoatomic cation channel activity 229 rec.
                                                        |   |__calcium channel activity(+) 70 rec.
                                                        |   |__ligand-gated monoatomic cation channel activity(+) 94 rec.
                                                        |   |__mechanosensitive monoatomic cation channel activity(+) 13 rec.
                                                        |   |__osmolarity-sensing monoatomic cation channel activity
                                                        |   |__potassium channel activity(+) 46 rec.
                                                        |   |__proton channel activity(+) 33 rec.
                                                        |   |__sodium channel activity(+) 50 rec.
                                                        |   |__temperature-gated cation channel activity 1 rec.
                                                        |   |__voltage-gated monoatomic cation channel activity(+) 41 rec.
                                                        |__temperature-gated ion channel activity 1 rec.
                                                        |   |__temperature-gated cation channel activity 1 rec.
                                                        |__voltage-gated monoatomic ion channel activity 52 rec.
                                                            |__NMDA glutamate receptor activity 3 rec.
                                                            |__voltage-gated monoatomic anion channel activity(+) 8 rec.
                                                            |__voltage-gated monoatomic cation channel activity(+) 41 rec.
                                                            |__voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
                                                            |__voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
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Is a monoatomic ion transmembrane transporter activity
channel activity
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Synonyms
  • "ion channel activity" BROAD
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