FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term inositol 1,4,5-trisphosphate-gated calcium channel activity ID (Ontology) GO:0005220 (Gene Ontology)
Definition Enables the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts.[ PubMed:28416699 PubMed:8660280 ]
Also Known As "inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity" ; "inositol-1,4,5-trisphosphate receptor activity" ; "InsP3 receptor" (for all, see Synonyms field below)
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Full annotation statements 
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 Genes
 inositol 1,4,5-trisphosphate-gated calcium channel activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | inositol 1,4,5-trisphosphate-gated calcium channel activity       1
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intracellularly ligand-gated monoatomic ion channel activity__
ligand-gated calcium channel activity_________________________|
                                                              intracellularly gated calcium channel activity
                                                               |__inositol 1,4,5-trisphosphate-gated calcium channel activity  1 rec.
                                                                   |__inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels
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Is a intracellularly gated calcium channel activity
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Synonyms
  • "inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity" EXACT
    "inositol-1,4,5-trisphosphate receptor activity" EXACT
    "InsP3 receptor" EXACT
    "IP3 receptor activity" EXACT
Secondary IDs
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