FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term gap junction channel activity ID (Ontology) GO:0005243 (Gene Ontology)
Definition A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes.[ ISBN:0815340729 ]
Also Known As "innexin channel activity"
Comment
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  QuickGO data     AmiGO data
Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       8
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 gap junction channel activity (all annotations which use CV term, excluding "NOT" statements)       1      8
     enables | gap junction channel activity       --       8
Spanning Tree (Parents/Children)
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  channel activity
   |__wide pore channel activity
       |__gap junction channel activity  9 rec.
           |__gap junction channel activity involved in cell communication by electrical coupling
           |   |__gap junction channel activity involved in cardiac conduction electrical coupling(+)
           |__gap junction hemi-channel activity 1 rec.
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Is a wide pore channel activity
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Synonyms
  • "connexin" RELATED
    "innexin" NARROW
    "innexin channel activity" EXACT
    "intercellular channel" BROAD
Secondary IDs
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Reactome:R-HSA-190681 "Connexin oligomerization in endoplasmic reticulum membrane"
Reactome:R-HSA-375330 "Connexin 45/Connexin 36 mediated neuronal gap junction communication"
Reactome:R-HSA-375339 "Pannexin 1/Pannexin2 mediated neuronal gap junction communication"
Reactome:R-HSA-375340 "Connexin 62 mediated neuronal gap junction communication"
Reactome:R-HSA-375342 "Connexin 36 mediated neuronal gap junction communication"