FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term voltage-gated calcium channel activity ID (Ontology) GO:0005245 (Gene Ontology)
Definition Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.[ ISBN:0815340729 ]
Also Known As "depolarization-activated voltage gated calcium channel activity" ; "depolarization-activated voltage-gated calcium channel" ; "depolarization-activated voltage-gated calcium channel activity" (for all, see Synonyms field below)
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 voltage-gated calcium channel activity (all annotations which use CV term, excluding "NOT" statements)
     enables | voltage-gated calcium channel activity       --
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voltage-gated monoatomic ion channel activity
 |__voltage-gated monoatomic cation channel activity__
monoatomic cation channel activity                    |
 |__calcium channel activity__________________________|
 |__voltage-gated monoatomic cation channel activity__|
calcium ion transmembrane transporter activity        |
 |__calcium channel activity__________________________|
                                                      voltage-gated calcium channel activity  10 rec.
                                                       |__high voltage-gated calcium channel activity 3 rec.
                                                       |__intermediate voltage-gated calcium channel activity
                                                       |__light-activated voltage-gated calcium channel activity
                                                       |__low voltage-gated calcium channel activity 2 rec.
                                                       |__voltage-gated calcium channel activity involved in cardiac muscle cell action potential
                                                       |   |__voltage-gated calcium channel activity involved in AV node cell action potential
                                                       |   |__voltage-gated calcium channel activity involved in bundle of His cell action potential
                                                       |   |__voltage-gated calcium channel activity involved SA node cell action potential
                                                       |__voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels
                                                       |__voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels
                                                           |__voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
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Is a calcium channel activity
voltage-gated monoatomic cation channel activity
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Synonyms
  • "depolarization-activated calcium channel" BROAD
    "depolarization-activated voltage gated calcium channel activity" EXACT
    "depolarization-activated voltage-gated calcium channel" EXACT
    "depolarization-activated voltage-gated calcium channel activity" EXACT
    "dihydropyridine-sensitive calcium channel activity" NARROW
    "voltage gated calcium channel activity" EXACT
    "voltage-dependent calcium channel activity" EXACT
    "voltage-gated calcium ion channel activity" EXACT
    "voltage-sensitive calcium channel" EXACT
Secondary IDs
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Reactome:R-HSA-265645 "Calcium Influx through Voltage-gated Calcium Channels"
Reactome:R-HSA-5577213 "LTCC multimer transports Ca2+ from extracellular region to cytosol"
Reactome:R-HSA-9701055 "TRPA1 tetramer transports Ca2+ from extracellular region to cytosol"
Reactome:R-HSA-9701141 "TRPV1 transports Ca2+ from extracellular region to cytosol"
Reactome:R-HSA-9905934 "CaV3.2 (CACNA1H:CACNA2D1:CACNB1,2,3:CACNG7) transports calcium from the extracellular region to the cytosol"