FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

voltage-gated sodium channel activity

ID (Ontology)

GO:0005248 (Gene Ontology)

Definition

Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.[ ISBN:0815340729 ]

Also Known As

"voltage gated sodium channel activity" ; "voltage-dependent sodium channel activity" ; "voltage-gated sodium ion channel activity" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
voltage-gated sodium channel activity (all annotations which use CV term, excluding "NOT" statements)
enables \| voltage-gated sodium channel activity	--

Spanning Tree (Parents/Children)

monoatomic cation channel activity_____________
sodium ion transmembrane transporter activity__|
                                               sodium channel activity
                                                |__voltage-gated sodium channel activity  5 rec.
                                                    |__mechanosensitive voltage-gated sodium channel activity
                                                    |__voltage-gated sodium channel activity involved in cardiac muscle cell action potential
                                                        |__voltage-gated sodium channel activity involved in AV node cell action potential
                                                        |__voltage-gated sodium channel activity involved in bundle of His cell action potential
                                                        |__voltage-gated sodium channel activity involved in Purkinje myocyte action potential
                                                        |__voltage-gated sodium channel activity involved in SA node cell action potential

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	sodium channel activity
Part of
Synonyms & Secondary IDs
Synonyms
	"voltage gated sodium channel activity" EXACT "voltage-dependent sodium channel activity" EXACT "voltage-gated sodium ion channel activity" EXACT "voltage-sensitive sodium channel" EXACT
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-5576895 "SCNAs:SNCBs transport Na+ from extracellular region to cytosol"