FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term calcium channel activity ID (Ontology) GO:0005262 (Gene Ontology)
Definition Enables the energy-independent facilitated diffusion of a calcium ion through a transmembrane aqueous pore or channel.[ ISBN:0815340729 ]
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      35
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 calcium channel activity (all annotations which use CV term, excluding "NOT" statements)       7     35
     contributes_to | calcium channel activity       --       3
     enables | calcium channel activity       --      35
Spanning Tree (Parents/Children)
Only view relationship: 
monoatomic ion channel activity
 |__monoatomic cation channel activity________________
monoatomic cation transmembrane transporter activity  |
 |__monoatomic cation channel activity________________|
metal ion transmembrane transporter activity          |
 |__calcium ion transmembrane transporter activity____|
                                                      calcium channel activity  70 rec.
                                                       |__ligand-gated calcium channel activity 20 rec.
                                                       |   |__glutamate-gated calcium ion channel activity 7 rec.
                                                       |   |__intracellularly gated calcium channel activity(+) 8 rec.
                                                       |   |__pH-gated calcium channel activity 1 rec.
                                                       |__store-operated calcium channel activity 7 rec.
                                                       |__stretch-activated, monoatomic cation-selective, calcium channel activity 2 rec.
                                                       |__voltage-gated calcium channel activity 10 rec.
                                                           |__high voltage-gated calcium channel activity 3 rec.
                                                           |__intermediate voltage-gated calcium channel activity
                                                           |__light-activated voltage-gated calcium channel activity
                                                           |__low voltage-gated calcium channel activity 2 rec.
                                                           |__voltage-gated calcium channel activity involved in cardiac muscle cell action potential(+)
                                                           |__voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels
                                                           |__voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels(+)
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Is a monoatomic cation channel activity
calcium ion transmembrane transporter activity
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Reactome:R-HSA-139854 "IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol"
Reactome:R-HSA-139855 "P2X1-mediated entry of Ca++ from plasma"
Reactome:R-HSA-210420 "Ca2+ influx through voltage gated Ca2+ channels"
Reactome:R-HSA-3295579 "TRPs transport extracellular Ca2+ to cytosol"
Reactome:R-HSA-8949145 "VDAC1,2,3 translocate calcium from the cytosol to the mitochondrial intermembrane space"
Reactome:R-HSA-8949178 "MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix"
Reactome:R-HSA-9663785 "CHRNA9:CHRNA10:AcCho transports Ca2+ from the extracellular region to the cytosol"
Reactome:R-HSA-9858800 "TRPV4 tetramer:CALM1:Ca2+ transports calcium ions (Ca2+) from the extracellular region to the cytosol"