FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term dicarboxylic acid transmembrane transporter activity ID (Ontology) GO:0005310 (Gene Ontology)
Definition Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 dicarboxylic acid transmembrane transporter activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | dicarboxylic acid transmembrane transporter activity       1
 NOT | enables | dicarboxylic acid transmembrane transporter activity       1
Spanning Tree (Parents/Children)
Only view relationship: 
  transmembrane transporter activity
   |__carboxylic acid transmembrane transporter activity
       |__dicarboxylic acid transmembrane transporter activity  40 rec.
           |__3-sulfino-L-alanine: proton, glutamate antiporter activity 1 rec.
           |__5-formyltetrahydrofolate transmembrane transporter activity
           |__alpha-ketoglutarate transmembrane transporter activity 2 rec.
           |   |__alpha-ketoglutarate:proton symporter activity
           |   |__citrate:2-oxoglutarate antiporter activity
           |   |__oxoglutarate:malate antiporter activity
           |__bilirubin transmembrane transporter activity
           |__C4-dicarboxylate transmembrane transporter activity 16 rec.
           |   |__aspartate:alanine antiporter activity
           |   |__D-aspartate transmembrane transporter activity
           |   |__fumarate transmembrane transporter activity(+)
           |   |__L-aspartate transmembrane transporter activity(+) 6 rec.
           |   |__malate transmembrane transporter activity(+) 5 rec.
           |   |__oxaloacetate transmembrane transporter activity 5 rec.
           |   |__succinate transmembrane transporter activity(+) 9 rec.
           |   |__tartrate transmembrane transporter activity(+)
           |__dicarboxylate:phosphate antiporter activity
           |__folic acid transmembrane transporter activity
           |   |__folate:monoatomic anion antiporter activity
           |   |__folic acid:proton symporter activity
           |__glutamate-gated receptor activity 16 rec.
           |   |__AMPA glutamate receptor activity
           |   |__glutamate-gated calcium ion channel activity 7 rec.
           |   |__kainate selective glutamate receptor activity 9 rec.
           |   |__NMDA glutamate receptor activity 3 rec.
           |__glutamate:gamma-aminobutyric acid antiporter activity
           |__isopropylmalate transmembrane transporter activity
           |__L-glutamate transmembrane transporter activity 8 rec.
           |   |__cystine:glutamate antiporter activity
           |   |__high-affinity L-glutamate transmembrane transporter activity 3 rec.
           |   |__L-glutamate uniporter activity
           |   |__L-glutamate:proton antiporter activity(+) 1 rec.
           |__malonate(1-) transmembrane transporter activity
           |   |__sodium:malonate symporter activity
           |__methotrexate transmembrane transporter activity
           |__oxalate transmembrane transporter activity 3 rec.
           |   |__oxalate:chloride antiporter activity
           |__secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
           |__sodium:dicarboxylate symporter activity 5 rec.
               |__glutamate:sodium symporter activity(+) 5 rec.
               |__high-affinity sodium:dicarboxylate symporter activity
               |__low-affinity sodium:dicarboxylate symporter activity
               |__malate:sodium symporter activity
               |__sodium:malonate symporter activity
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Is a carboxylic acid transmembrane transporter activity
Part of
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Synonyms
  • "dicarboxylate (succinate/fumarate/malate) antiporter activity" RELATED
    "dicarboxylate carrier" NARROW
    "dicarboxylic acid permease activity" RELATED
    "sodium:dicarboxylate/tricarboxylate symporter activity" NARROW
Secondary IDs
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Reactome:R-HSA-1614546 "Sulfate is exported to the cytosol in exchange for dicarboxylate"
Reactome:R-HSA-372843 "SLC25A10 mediates exchange of malate and phosphate"