FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term high-affinity L-glutamate transmembrane transporter activity ID (Ontology) GO:0005314 (Gene Ontology)
Definition Enables the transfer of glutamate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 high-affinity L-glutamate transmembrane transporter activity (all annotations which use CV term, excluding "NOT" statements)
     enables | high-affinity L-glutamate transmembrane transporter activity
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amino acid:sodium symporter activity
 |__glutamate:sodium symporter activity_______________
dicarboxylic acid transmembrane transporter activity  |
 |__L-glutamate transmembrane transporter activity____|
acidic amino acid transmembrane transporter activity  |
 |__L-glutamate transmembrane transporter activity____|
L-amino acid transmembrane transporter activity       |
 |__L-glutamate transmembrane transporter activity____|
sodium:dicarboxylate symporter activity               |
 |__glutamate:sodium symporter activity_______________|
                                                      high-affinity L-glutamate transmembrane transporter activity  3 rec.
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Is a L-glutamate transmembrane transporter activity
glutamate:sodium symporter activity
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Synonyms
  • "high-affinity glutamate transmembrane transporter activity" BROAD
    "high-affinity glutamate transporter activity" BROAD
Secondary IDs
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Reactome:R-HSA-210404 "SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+"
Reactome:R-HSA-428015 "SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol"
Reactome:R-HSA-5625015 "Defective SLC1A3 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol"
Reactome:R-HSA-5625029 "SLC1A1 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol"