FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term serotonin:sodium:chloride symporter activity ID (Ontology) GO:0005335 (Gene Ontology)
Definition Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: serotonin(out) + Na+(out) + Cl-(out) = serotonin(in) + Na+(in)+ Cl-(in).[ PubMed:21752877 PubMed:22519513 ]
Also Known As "serotonin transmembrane transporter activity" ; "sodium/serotonin symporter activity"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
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Relevant FlyBase reports
 Genes
 serotonin:sodium:chloride symporter activity (all annotations which use CV term, excluding "NOT" statements)       3
     enables | serotonin:sodium:chloride symporter activity       3
Spanning Tree (Parents/Children)
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monoatomic anion:sodium symporter activity
 |__sodium:chloride symporter activity____________
chloride:monoatomic cation symporter activity     |
 |__sodium:chloride symporter activity____________|
active transmembrane transporter activity         |
 |__monoamine transmembrane transporter activity__|
                                                  serotonin:sodium:chloride symporter activity  3 rec.
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Is a monoamine transmembrane transporter activity
sodium:chloride symporter activity
Part of
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Synonyms
  • "serotonin transmembrane transporter activity" EXACT
    "serotonin:sodium symporter activity" RELATED
    "sodium/serotonin symporter activity" EXACT
Secondary IDs
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Reactome:R-HSA-444008 "SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol"
RHEA:51196
TC:2.A.22.1.1