FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term iron ion transmembrane transporter activity ID (Ontology) GO:0005381 (Gene Ontology)
Definition Enables the transfer of iron (Fe) ions from one side of a membrane to the other.
Also Known As "iron cation channel activity" ; "iron channel activity" ; "iron transporter activity" (for all, see Synonyms field below)
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 iron ion transmembrane transporter activity (all annotations which use CV term, excluding "NOT" statements)       3
     enables | iron ion transmembrane transporter activity       3
Spanning Tree (Parents/Children)
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  metal ion transmembrane transporter activity
   |__transition metal ion transmembrane transporter activity
       |__iron ion transmembrane transporter activity  3 rec.
           |__ferric iron transmembrane transporter activity
           |   |__ABC-type ferric iron transporter activity
           |   |__high-affinity ferric iron transmembrane transporter activity
           |   |__low-affinity ferric iron ion transmembrane transporter activity
           |__ferrous iron transmembrane transporter activity 1 rec.
               |__high-affinity ferrous iron transmembrane transporter activity
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Is a transition metal ion transmembrane transporter activity
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Synonyms
  • "iron cation channel activity" EXACT
    "iron channel activity" EXACT
    "iron transporter activity" EXACT
    "multicopper ferroxidase iron transport mediator activity" RELATED
    "transmembrane iron ion permease activity" EXACT
    "transmembrane iron permease activity" EXACT
    "zinc, iron permease activity" RELATED
Secondary IDs
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Reactome:R-HSA-435349 "SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol"
Reactome:R-HSA-5623558 "Defective SLC11A2 does not cotransport Fe2+, H+ from extracellular region to cytosol"
Reactome:R-HSA-5655733 "Defective SLC40A1 does not transport Fe2+ from cytosol to extracellular region"
Reactome:R-HSA-904830 "SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region"
Reactome:R-HSA-917936 "MCOLN1 transports Fe2+ from endosome lumen to cytosol"