FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

iron ion transmembrane transporter activity

ID (Ontology)

GO:0005381 (Gene Ontology)

Definition

Enables the transfer of iron (Fe) ions from one side of a membrane to the other.

Also Known As

"iron cation channel activity" ; "iron channel activity" ; "iron transporter activity" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
iron ion transmembrane transporter activity (all annotations which use CV term, excluding "NOT" statements)
enables \| iron ion transmembrane transporter activity

Spanning Tree (Parents/Children)

  metal ion transmembrane transporter activity
   |__transition metal ion transmembrane transporter activity
       |__iron ion transmembrane transporter activity  3 rec.
           |__ferric iron transmembrane transporter activity
           |   |__ABC-type ferric iron transporter activity
           |   |__high-affinity ferric iron transmembrane transporter activity
           |   |__low-affinity ferric iron ion transmembrane transporter activity
           |__ferrous iron transmembrane transporter activity 1 rec.
               |__high-affinity ferrous iron transmembrane transporter activity

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	transition metal ion transmembrane transporter activity
Part of
Synonyms & Secondary IDs
Synonyms
	"iron cation channel activity" EXACT "iron channel activity" EXACT "iron transporter activity" EXACT "multicopper ferroxidase iron transport mediator activity" RELATED "transmembrane iron ion permease activity" EXACT "transmembrane iron permease activity" EXACT "zinc, iron permease activity" RELATED
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-435349 "SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol" Reactome:R-HSA-5623558 "Defective SLC11A2 does not cotransport Fe2+, H+ from extracellular region to cytosol" Reactome:R-HSA-5655733 "Defective SLC40A1 does not transport Fe2+ from cytosol to extracellular region" Reactome:R-HSA-904830 "SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region" Reactome:R-HSA-917936 "MCOLN1 transports Fe2+ from endosome lumen to cytosol"