FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term P-type sodium:potassium-exchanging transporter activity ID (Ontology) GO:0005391 (Gene Ontology)
Definition Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in).[ EC:7 ]
Also Known As "P-type sodium:potassium-exchanging ATPase activity" ; "sodium/potassium-exchanging ATPase activity" ; "sodium/potassium-transporting ATPase activity" (for all, see Synonyms field below)
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 P-type sodium:potassium-exchanging transporter activity (all annotations which use CV term, excluding "NOT" statements)       2      2
     enables | P-type sodium:potassium-exchanging transporter activity       --       2
Spanning Tree (Parents/Children)
Only view relationship: 
potassium ion transmembrane transporter activity
 |__P-type potassium transmembrane transporter activity______________
sodium ion transmembrane transporter activity                        |
 |__P-type sodium transporter activity_______________________________|
P-type ion transporter activity                                      |
 |__P-type sodium transporter activity_______________________________|
 |__P-type potassium transmembrane transporter activity______________|
ATPase-coupled monoatomic cation transmembrane transporter activity  |
 |__P-type sodium transporter activity_______________________________|
 |__P-type potassium transmembrane transporter activity______________|
                                                                     P-type sodium:potassium-exchanging transporter activity  4 rec.
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Is a P-type sodium transporter activity
P-type potassium transmembrane transporter activity
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Synonyms
  • "Na(+)/K(+)-ATPase activity" RELATED[ EC:7 ]
    "Na(+)/K(+)-exchanging ATPase activity" RELATED[ EC:7 ]
    "Na+,K+-ATPase activity" RELATED[ EC:7 ]
    "Na+/K+-ATPase activity" RELATED[ EC:7 ]
    "Na+/K+-exchanging ATPase activity" RELATED[ EC:7 ]
    "Na,K-activated ATPase activity" RELATED[ EC:7 ]
    "P-type sodium:potassium-exchanging ATPase activity" EXACT
    "sodium pump" BROAD[ EC:7 ]
    "sodium/potassium-exchanging ATPase activity" EXACT
    "sodium/potassium-transporting ATPase activity" EXACT
    "sodium:potassium exchanging ATPase activity" EXACT
    "sodium:potassium-exchanging ATPase activity" EXACT
Secondary IDs
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EC:7.2.2.13
MetaCyc:3.6.3.9-RXN
Reactome:R-HSA-936897 "ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+"
RHEA:18353
TC:3.A.3.1.1
Wikipedia:ATPase\,_Na%2B/K%2B_transporting\,_alpha_1