FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term solute:inorganic anion antiporter activity ID (Ontology) GO:0005452 (Gene Ontology)
Definition Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion(out) + solute(in) = inorganic anion (in) + solute(out).
Also Known As"inorganic anion exchanger activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 solute:inorganic anion antiporter activity (all annotations which use CV term, excluding "NOT" statements)
     enables | solute:inorganic anion antiporter activity
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  secondary active transmembrane transporter activity
   |__antiporter activity
       |__solute:inorganic anion antiporter activity  10 rec.
           |__chloride:bicarbonate antiporter activity 1 rec.
           |   |__sodium,bicarbonate:chloride antiporter activity
           |__chloride:proton antiporter activity 3 rec.
           |__dicarboxylate:phosphate antiporter activity
           |__organophosphate:phosphate antiporter activity 3 rec.
           |   |__ADP:phosphate antiporter activity
           |   |__ATP:phosphate antiporter activity 1 rec.
           |   |__glycerol-phosphate:phosphate antiporter activity
           |   |__glycerone phosphate:phosphate antiporter activity
           |   |__hexose-phosphate:phosphate antiporter activity(+) 2 rec.
           |   |__phosphoenolpyruvate:phosphate antiporter activity
           |   |__triose-phosphate:phosphate antiporter activity(+)
           |__oxalate:chloride antiporter activity
           |__sulfate:bicarbonate antiporter activity
           |__sulfate:chloride antiporter activity
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Synonyms
  • "inorganic anion exchanger activity" EXACT
Secondary IDs
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Reactome:R-HSA-1237038 "SLC4A1 exchanges cytosolic HCO3- for extracellular Cl-"
Reactome:R-HSA-1247665 "SLC4A1 exchanges cytosolic Cl- for extracellular HCO3-"
Reactome:R-HSA-425482 "SLC4A1,2,3 exchanges HCO3- for Cl-"
Reactome:R-HSA-425577 "Na+-driven Cl-/HCO3- exchanger transport"
Reactome:R-HSA-427666 "SLC26A3,6 exchange Cl- for HCO3-"
Reactome:R-HSA-5627737 "SLC26A3 does not exchange Cl- for HCO3-"
Reactome:R-HSA-5656248 "Defective SLC4A1 does not exchange Cl- for HCO3- (in erythrocytes)"