FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term DNA replication factor A complex ID (Ontology) GO:0005662 (Gene Ontology)
Definition A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa.[ PubMed:9242902 ]
Also Known As"replication protein A" ; "RPA"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
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 DNA replication factor A complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | DNA replication factor A complex
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nucleus
 |__nuclear protein-containing complex__
replisome                               |
 |__nuclear replisome___________________|
protein-containing complex              |
 |__nuclear protein-containing complex__|
nuclear replication fork                |
 |__nuclear replisome___________________|
nuclear protein-containing complex      |
 |__nuclear replisome___________________|
                                        DNA replication factor A complex  3 rec.
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Is a nuclear protein-containing complex
Part of nuclear replisome
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Synonyms
  • "replication protein A" EXACT
    "RPA" EXACT
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Wikipedia:Replication_protein_A