FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term eukaryotic translation initiation factor 2B complex ID (Ontology) GO:0005851 (Gene Ontology)
Definition A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon.[ PubMed:9438375 ]
Also Known As"eIF-2B" ; "eif2B"
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 eukaryotic translation initiation factor 2B complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | eukaryotic translation initiation factor 2B complex
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intracellular anatomical structure
 |__cytoplasm__________________________________
cellular anatomical structure                  |
 |__cytoplasm__________________________________|
intracellular protein-containing complex       |
 |__guanyl-nucleotide exchange factor complex__|
                                               eukaryotic translation initiation factor 2B complex  6 rec.
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Is a guanyl-nucleotide exchange factor complex
Part of cytoplasm
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Synonyms
  • "eIF-2B" EXACT
    "eif2B" EXACT
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