FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

phosphatidylinositol 3-kinase complex

ID (Ontology)

GO:0005942 (Gene Ontology)

Definition

A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too.[ PubMed:24587488 ]

Also Known As

"1-phosphatidylinositol 3-kinase complex" ; "phosphoinositide 3-kinase complex" ; "PI3K complex"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
phosphatidylinositol 3-kinase complex (all annotations which use CV term, excluding "NOT" statements)
part_of \| phosphatidylinositol 3-kinase complex

Spanning Tree (Parents/Children)

membrane
 |__extrinsic component of membrane_________________________________
 |__membrane protein complex________________________________________|
protein-containing complex                                          |
 |__membrane protein complex________________________________________|
cellular anatomical structure                                       |
 |__extrinsic component of membrane_________________________________|
transferase complex                                                 |
 |__transferase complex, transferring phosphorus-containing groups__|
                                                                    phosphatidylinositol 3-kinase complex  9 rec.
                                                                     |__phosphatidylinositol 3-kinase complex, class I 3 rec.
                                                                     |   |__phosphatidylinositol 3-kinase complex, class IA 3 rec.
                                                                     |   |__phosphatidylinositol 3-kinase complex, class IB
                                                                     |__phosphatidylinositol 3-kinase complex, class II
                                                                     |__phosphatidylinositol 3-kinase complex, class III 6 rec.
                                                                         |__phosphatidylinositol 3-kinase complex, class III, type I 5 rec.
                                                                         |__phosphatidylinositol 3-kinase complex, class III, type II 4 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	transferase complex, transferring phosphorus-containing groups membrane protein complex
Part of	extrinsic component of membrane
Synonyms & Secondary IDs
Synonyms
	"1-phosphatidylinositol 3-kinase complex" EXACT "phosphoinositide 3-kinase complex" EXACT "PI3-kinase p85-subunit alpha- PI3-kinase p110 complex" NARROW "PI3K complex" EXACT "PIK3C3-PIK3R4 complex" NARROW "PIK3CA-PIK3R1 complex" NARROW
Secondary IDs

External Crossreferences & Linkouts