FB2026_03 , released September 17, 2026
CV Term Report
Help Close All Open All
General Information
Term pentose-phosphate shunt ID (Ontology) GO:0006098 (Gene Ontology)
Definition The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate).[ ISBN:0198506732 ]
Also Known As"hexose monophosphate pathway" ; "pentose phosphate pathway" ; "pentose phosphate shunt" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

    • Results list data from multiple species. Choose a record type above to open its HitList.
Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 pentose-phosphate shunt (all annotations which use CV term, excluding "NOT" statements)
     involved_in | pentose-phosphate shunt       --
Spanning Tree (Parents/Children)
Only view relationship:
Vocabulary search 
generation of precursor metabolites and energy
 |__NADPH regeneration_____________________
NADP+ metabolic process                    |
 |__NADPH regeneration_____________________|
organophosphate metabolic process          |
 |__glucose 6-phosphate metabolic process__|
carbohydrate derivative metabolic process  |
 |__glucose 6-phosphate metabolic process__|
                                           pentose-phosphate shunt  10 rec.
                                            |__pentose-phosphate shunt, non-oxidative branch 5 rec.
                                            |__pentose-phosphate shunt, oxidative branch 3 rec.
                                            |__regulation of pentose-phosphate shunt 1 rec.
                                                |__negative regulation of pentose-phosphate shunt
                                                |__positive regulation of pentose-phosphate shunt 1 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a NADPH regeneration
glucose 6-phosphate metabolic process
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "hexose monophosphate pathway" EXACT
    "pentose phosphate pathway" EXACT
    "pentose phosphate shunt" EXACT
    "pentose-phosphate pathway" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
KEGG_PATHWAY:map00030
MetaCyc:PENTOSE-P-PWY
Reactome:R-HSA-71336 "Pentose phosphate pathway"
Wikipedia:Pentose_phosphate_pathway